y 7\o � 7�n�n�s 7�yxn�~r
progress in neuro-psychopharmacology & biological psychiatry 72017.107qdynamic split g-quadruplex programmed reversible nanodevice
reversible nanodevice7zproximity hybridization-mediated isothermal
exponential amplification for ultrasensitive
electrochemical protein detection7%international journal of nanomedicine7zproximity hybridization-mediated isothermal
exponential amplification for ultrasensitive
electrochemical protein detection7%international journal of nanomedicine7planta medicinalmedicinal chemistry research7
n�~7bsynthesis, cytotoxicity and pro-apoptosis of novel benzoisoindolin hydrazones as anticancer agents7^synthesis and bioactivity of pyrazolo [1,5-a] pyrimidine derivatives as novel c-met inhibitors7_synthesis and identification of cytotoxic diphyllin glycosides as vacuolar h -atpase inhibitors7'european journal of medicinal chemistry7t1,3,5-triazine inhibitors of histone deacetylases: synthesis and biological activity7>synthesis and bioevaluation of novel analogues of justicidin a7"chemical & pharmaceutical bulletin7�synthesis and evaluation of aroylthiourea derivatives of 4-�-amino-4'- o-demethyl-4-desoxypodophyllotoxin as novel topoisomerase ii inhibitors7'european journal of medicinal chemistry7vsynthesis and antitumor activity of novel aroylthiourea derivatives of podophyllotoxin7investigational new drugs7$chinese journal of organic chemistry7qsynthesis and bioevaluation of novel arylnaphthalene lignans as anticancer agents7dhy-1 induce g2/m cell cycle arrest in human colon cancer cells via atr-chk1-cdc25c and weel pathways7cancer science72017.107antidepressant-like effects of tetrahydroxystilbene glucoside in mice: involvement of bdnf signaling cascade in the hippocampus7vactions of brain-derived neurotrophic factor and glucocorticoid stress in neurogenesis7
int j mol sci7�resveratrol ameliorates chronic unpredictable mild stress-induced depression-like behavior: involvement of the hpa axis, inflammatory markers, bdnf, and wnt/�-catenin pathway in rats7neuropsychiatr dis treat7yang xh, song sq, xu y7�targeting the endocannabinoid/cb1 receptor system for treating major depression through antidepressant activities of curcumin and dexanabinol-loaded solid lipid nanoparticles7�the antidepressant-like effects of biperiden may involve bdnf/trkb signaling-mediated bicc1 expression in the hippocampus and prefrontal cortex of mice7]zhou d, zhang z, liu l, li c, li m, yu h, cai x, sun x, shen x, wang j, geng j, wang c, shi y7gantidepressant-like effects of ginsenoside rg5 in mice: involving of hippocampus bdnf signaling pathway7"xu d, wang c, zhao w, gao s, cui z7lp7c3 attenuates the scopolamine-induced memory impairments in c57bl/6j mice.7�piracetam facilitates the anti-amnesic but not anti-diabetic activity of metformin in experimentally induced type-2 diabetic encephalopathic rats7cell death dis7xmitochondrial permeability transition pore as a suitable targ e t for neuroprotective agents against alzheimer's disease74you z, yao q, shen j, gu z, xu h, wu z, chen c, li l7_[�v�h7�dihydromyricetin attenuates myocardial hypertrophy induced by transverse aortic constriction via oxidative stress inhibition and sirt3 pathway enhancement7�attenuating effects of dihydromyricetin on angiotensin ii-induced rat cardiomyocyte hypertrophy related to antioxidative activity in a no-dependent manner 7
pharm biol�prostacyclin analogue beraprost inhibits cardiac fibroblast proliferation depending on prostacyclin receptor activation through a tgf �-smad signal pathway7plos one7�attenuating effects of ganoderma lucidum polysaccharides on myocardial collagen cross-linking relates to advanced glycation end product and antioxidant enzymes in high-fat-diet and streptozotocin-induced diabetic rats 7carbohydr polym7_[�v�h�synergistic attenuation of myocardial fibrosis in spontaneously hypertensive rats by joint treatment with benazepril and candesartan 7j cardiovasc pharmacol.7eur j pharmacol7_[�v�h73the versatile effects of dihydromyricetin in health75evidence-based complementary and alternative medicine7,li, hongliang; li, qisheng; liu, zhaowen; i{.�dihydromyricetin protects against lipopolysaccharide-induced cardiomyocyte injury through the toll-like receptor-4/nuclear factor-kappa b pathway7molecular medicine reports �(zhou, meng-qiao; shao, ling; wu, jing; i{7�dihydromyricetin protects human umbilical vein endothelial cells from injury through erk and akt mediated nrf2/ho-1 signaling pathway 7
apoptosis luo, yun; lu, shan; dong, xi; i{7win vitro inhibitory effects of dihydromyricetin on human liver cytochrome p450 enzymes 7pharmaceutical biology ��$liu, lu; sun, sen; rui, hongbing; i{.7hanti-inflammatory effects of dihydromyricetin in a mouse model of asthmamolecular medicine reports (xu, bin; huang, shuran; wang, caiying; i{pantidepressant-like effects of ginsenoside rg3 in mice via activation of the hippocampal bdnf signaling cascade journal of natural medicines you, zhengchen; yao, qi; shen, jianhong; i{.3the versatile effects of dihydromyricetin in healthbdihydromyricetin protects against diabetic cardiomyopathy in streptozotocin-induced diabetic mice biomed research interna< tional7!
wu, bin; lin, jie; luo, jian; i{. 7{antidepressant-like effects of fenofibrate in mice via the hippocampal brain-derived neurotrophic factor signalling pathway british journal of pharmacology 7'jiang, bo; wang, ying-jie; wang, hao; i{7kdetermination of dihydromyricetin in rat plasma by lc-ms/ms and its application to a pharmacokinetic study 7pharmaceutical biology ��7"liu, lu; yin, xiaolan; wang, xu; i{7�prostacyclin analogue beraprost inhibits cardiac fibroblast proliferation depending on prostacyclin receptor activation through a tgf �-smad signal pathway7plos one7htransforming growth factor beta: a potential biomarker and therapeutic target of ventricular remodeling 7
oncotarget ��7&ma, yuan; zou, hai; zhu, xing-xing; i{.7�dibutyryl-camp attenuates pulmonary fibrosis by blocking myofibroblast differentiation via pka/creb/cbp signaling in rats with silicosis7respiratory research7$liu, yan; xu, hong; geng, yucong; i{.7�attenuating effects of ganoderma lucidum polysaccharides on myocardial collagen cross-linking relates to advanced glycation end product and antioxidant enzymes in high-fat-diet and streptozotocin-induced diabetic rats 7carbohydr polym7�purification and identification of rambutan (nephelium lappaceum) peel phenolics with evaluation of antioxidant and antiglycation activities invitro75international journal of food science and technology 7'zhuang yongliang; ma qingyu; guo yan; i{7�preparation, characterisation, antioxidant and antiglycation activities of the novel polysaccharides from the pileus of dictyophora rubrovolvata 7,sun, liping; bao, changjun; chang, weidan; i{7�synergistic attenuation of myocardial fibrosis in spontaneously hypertensive rats by joint treatment with benazepril and candesartan 7j cardiovasc pharmacol.7�reduction in skeletal muscle fibrosis of spontaneously hypertensive rats after laceration by microrna targeting angiotensin ii receptor 7 plos one 7kstilhano, roberta sessa; samoto, vivian yochiko; silva, leonardo martins; i{7cbio-inspired protein-based nanoformulations for cancer theranostics7 2018.4.277lfabrication of gold nanorods with tunable longitudinal surface plasmon resonance peaks by reductive dopamine7langmuir7zsize-dependent facilitation of cancer cell targeting by proteins adsorbed on nanoparticles7"acs applied materials & interfaces7lfabrication of gold nanorods with tunable longitudinal surface plasmon resonance peaks by reductive dopamine7[accelerating gold nanorod synthesis with nanomolar concentrations of poly(vinylpyrrolidone)7langmuir7f requejo, katherinne i.liopo, anton v.derry, paul j.zubarev, eugene r.7�decorating silver nanoparticles on electrospun cellulose nanofibers through a facile method by dopamine and ultraviolet irradiation7 cellulose7" gaminian, hamdam; montazer, majid7tlight-triggered assembly of gold nanorods based on photoisomerization of spiropyrans7chemistry letters7' mochizuki, chihiro; shinmori, hideyuki7�one-pot anchoring of pd nanoparticles on nitrogendoped carbon through dopamine self-polymerization and activity in the electrocatalytic methanol oxidation reaction7
chemsuschem 7�seedless synthesis of monodispersed gold nanorods with remarkably high yield: synergistic effect of template modification and growth kinetics regulation7chemistry-a european journal 7lunderstanding the seed-mediated growth of gold nanorods through a fractional factorial design of experiments7dsynthesis and tuning of gold nanorods with surface plasmon resonance7optical materials 7`short peptide amphiphile cage facilitate engineering of gold nanoparticles under the laser field7chemistryselect 7dseedless synthesis of gold nanorods with longitudinal surface plasmon resonance wavelength of 1200nm7spectroscopy letters 7$ li, min; qian, linyong; han, caiqin7�gold nanorod-based poly(lactic-co-glycolic acid) with manganese dioxide core-shell structured multifunctional nanoplatform for cancer theranostic applications7(international journal of nanomedicine 7"acs applied materials & interfaces7
2018.10.257��sfpn7
n�~7
�n:s7
jcrr:s7
ğ��7
ğ��7
ςؚf7
�v:s7
ςؚf720130607chemotherapy7�medicinal uses, pharmacology, and phytochemistry of convolvulaceae plants with central nervous system efficacies: a systematic review7phytotherapy research72018.0573.34972017.127�the ketone body metabolite �-hydroxybutyrate induces an antidepression-associated ramification of microglia via hdacs inhibition-triggered akt-small rhogtpase activation.7glia7sodium butyrate triggers a functional elongation of microglial process via akt-small rhogtpase activation and hdacs inhibition.7eur j pharmacol7sci7qdynamic changes in hippocampal microglia contribute to depressive-like behavior induced by early social isolation7�tauroursodeoxycholic acid produces antidepressant-like effects in a chronic unpredictable stress model of depression via attenuation of neuroinflammation, oxido-nitrosative stress, and endoplasmic reticulum stress7fundam clin pharmacol7�development of novel �-carboline-based hydroxamate derivatives as hdac inhibitors with antiproliferative and antimetastatic activities in human cancer cells7eur. j. med. chem720100987�development of novel amino-quinoline- 5,8-dione derivatives as nad(p)h: quinone oxidoreductase 1 (nqo1) inhibitors with potent antiproliferative activities.7�a novel harmine derivative, n-(4-(hydroxycarbamoyl)benzyl)-1-(4- methoxyphenyl)-9h-pyrido[3,4-b]indole-3-carboxamide (hbc), as histone deacetylase inhibitor: in vitro antiproliferat< ion, apoptosis induction, cell cycle arrest, and antimetastatic effects.7eur j pharmacol.7org. biomol. chem.,7org. biomol. chem.,7�comparative metabolism of two major compounds in fructus corni extracts by gut microflora from normal and chronic nephropathy rats in vitro by
uplc-q-tof/ms7journal of chromatography b7�polysaccharides from chrysanthemum morifolium ramat ameliorate colitis rats via regulation of the metabolic profiling and nf-k b/tlr4 and il-6/jak2/stat3 signaling pathways7frontiers in pharmacology7�uplc-q-tof/ms-based metabolic profiling comparison of four major bioactive components in normal and ckd rat plasma, urine and feces following oral administration of cornus officinalis sieb and rehmannia
glutinosa libosch herb couple extract71journal of pharmaceutical and biomedical analysis7�straightforward synthesis of quinolines from enones and 2-aminobenzyl alcohols using an iridium-catalyzed transfer hydrogenative strategy 7 organic & biomolecular chemistry7�2,3,4',5-tetrahydroxystilbene-2-o-�-d-glycoside attenuates atherosclerosis in apolipoprotein e-deficient mice: role of reverse cholesterol transport.7/canadian journal of physiology and pharmacology720080557qdihydromyricetin ameliorates foam cell formation via lxr�-abca1/abcg1-dependent cholesterol efflux in macrophages7biomedicine & pharmacotherapy7 european journal of pharmacology7pharmacological research
7
2018.05.207$cellular physiology
and biochemistry7
2018.08.297chemical communications7
n:s7xsynthesis and assessment of novel anti-chlamydial benzylidene acylhydrazides derivatives7$ letters in drug design & discovery 7�development and evaluation of thermo-sensitive hydrogel system with nanocomplexes for prolonged subcutaneous delivery of enoxaparin7/journal of drug
delivery science and technology72018.9.47|hippocampal ppar� is a novel therapeutic target for depression and mediates the antidepressant actions of fluoxetine in mice7br j pharmacol7uhydrogen sulfide pretreatment improves mitochondrial function in myocardial hypertrophy via a sirt3-dependent manner.7br j pharmacol7
_[�v�h7eprotein s-sulfhydration by hydrogen sulfide in cardiovascular system.7
int j mol sci7frontiers in pharmacology7 2018.4.277
ςؚf7
n�~7vve-albumin core-shell nanoparticles for paclitaxel delivery to treat mdr breast cancer7 molecules7201607673.0987ion the hypoxic tumor targeting ability of two chitosan micelles loaded with oil-soluble cdse quantum dots7pharm dev technol.7q_�t�vp[7cns neurosci ther7br j pharmacol7[antidepressant-like effects of gm1 ganglioside involving the bdnf signaling cascade in mice7int j neuropsychopharmacol7twy14643 produces anti-depressant-like effects in mice via the bdnf signaling pathway7psychopharmacology (berl)7jantinociceptive effects of sinomenine in a rat model of postoperative painbritish journal of pharmacologyscientific reportshantinociceptive effects of curcumin in a rat model of postoperative pain�characterization of metabolites of leonurine (scm-198) in rats after oral administration by liquid chromatography/tandem mass spectrometry and nmr spectrometrythe scientific world journalbrain research^ investigation of piceid metabolites in rat by liquid chromatography tandem mass spectrometry.7 journal of chromatography b7
h�^�7yeffects of 2,3,4 ,5-tetrahydroxystilbene-2-0-�-d-glucoside on vascular
endothelial dysfunction in atherogenic-diet rats
�inhibition of calcium-calmodulin-dependent kinase ii suppress cardiac
fibroblast proliferation and extracellular matrix secretion
j cardiovasc pharmacol�ca2 d calmodulin-dependent protein kinase ii� orchestrates g-protein-coupled
receptor and electric �eld stimulation-induced cardiomyocyte hypertrophy
clin exp pharmacol physiol�2,3,4',5-tetrahydroxystilbene-2-0-beta-d-glucoside inhibits platelet-derived growth
factor-induced proliferation of vascular smooth muscle cells by regulating cell cycle.
clin exp pharmacol physiol.gelectrical field stimulation induces cardiac fibroblast proliferation through calcineurin-nfat pathway.can j physiol pharmacol.[mir-17-3p inhibits angiogenesis by downregulating flk-1 in the cell growth signal pathway.
j vasc res��-n-heterocyclic thiosemicarbazone fe(iii) complex: characterization of its antitumor activity and identification of anticancer mechanismeur j med chem.pdeveloping anticancer ferric prodrugs based on the n-donor residues of human serum albumin carrier iia subdomain
j med chem�rescue of cardiac failing and remodeling by inhibition of pp1� is associated with suppression of the asf-mediated splicing of camkii�[antidepressant-like effects of ginsenoside rg2 in a chronic mild stress model of depression�2,3,5,4 '-tetrahydroxystilbene-2-o-beta-d-glucoside protects murine hearts against ischemia/reperfusion injury by activating notch1/hes1 signaling and attenuating endoplasmic reticulum stressvdihydromyricetin attenuated ang ii induced cardiac fibroblasts proliferation related to inhibitory of oxidative stress _o���7s\�\���7
ğ��7
ğ��7
r�rn7
v�ёns7
�qj_7
��sfpn7
��sfpn7
�zsin7
ğ��7
r�rn7
v�ёns7
v�ёns7
��sfpn7
�ebh��7
_[�v�h7�q�r���7rfq�v7�y�ez���7u������7_l�l���7u�l71g�~s����7
n:s7
q_�t�vp[7
jcrr:s7�ns�s�7
2018.09.287 �v�q�ccg�sfn)r
߂�\7 n�yp�y�-^ y< �xܔm�tir-�n@�n}vˆ}v
ytir�svq�^(u v�tcdk�tdna�v� �tium�uir�svq6ry�e�l�t;so�(u�
�q�r7
ws�'yf[7
߂�\7
o�f[b�7
ws�'yf[7
�q�r7
o�f[b�7
n�y�nusirna��_g�~s|
ytir�s�^(u
7
ws�'yf[7
o�f[b�7
1g�~s�7zl 201510189351.67iantinociceptive effects of vitexin in a mouse model of postoperative painhantinociceptive effects of sinomenine in a rat model of neuropathic pain
�q�r7
n�~7 _[�v�h n�~
�y�ez7
jl�q�^7
�y�ez7
h�^�7
n�~7
߂�\7
ğ��7
�q�r78
0clinical and experimental pharmacology and physiology 077
�y�ez7 _o� 2,3,42 ,5-tetrahydroxystilbene-2-o-b-d-glucoside inhibits angiotensin
ii-induced cardiac �broblast proliferation via suppression of the reactive
oxygen species extracellular signal-regulated kinase 1/2 pathway
_o���
_[�v�h7��sfpn7_l�l71gn7nligustilide prevents cognitive impairment and attenuates neurotoxicity in d-galactose induced aging mice brain�ns�s�7!��syqqt,{n\o�n���\o���>e_dk�{�e�zvy�r�1u,g�neg3u��vy�r �7?
�mazur, marcelina;�gladkowski, witold;�srcek, visnja gaurina; i{>70
chiang, chien-min; wang, tzi-yuan; ke, an-ni; i{/7*
gao, qian; qiao, yuqian; shen, yanbing; i{)7
qiao, yuqian; shen, yanbing; huang, wei; i{*7'
ling, jin; yu, yingjia; feng, jianan; i{&7
���n_�e�z7< morin-sardin, stephanie; nodet, patrice; coton, emmanuel; i{72017.1070 chiang, chien-min; wang, tzi-yuan; ke, an-ni; i{7)
yang, feifei; zhou, jing; liu, chunyu; i{(7$
qiu, xin; yang, jiali; wang, wei; i{#7#
jiao, chenli; gao, feng; ou, li; i{"7'
tang, wenping; li, shiming; liu, yue; i{&7
���n_�e�z7�q�r7,heat shock proteins and the na /h exchanger7 channels 7cellular signalling 7j neuroinflammation7thypertonic saline infusion suppresses apoptosis of hippocampal cells in a rat model of cardiopulmonary resuscitation7�protective effect of 2,3,5,4'-tetrahydroxystilbene-2-o-beta-d-glucoside on aldosterone-induced cardiomyocytes injury via interfering p53 signaling pathway7tang, yu; hao, minghui7�ho-1 is essential for tetrahydroxystilbene glucoside mediated mitochondrial biogenesis and anti-inflammation process in lps-treated raw264.7 macrophages7[pp1� functionally augments the alternative splicing of camkii� through interaction with asf7cardiovascular pathology 7[antidepressant-like effects of ginsenoside rg2 in a chronic mild stress model of depression7brain research bulletin 7vdihydromyricetin attenuated ang ii induced cardiac fibroblasts proliferation related to inhibitory of oxidative stress7"european journal of pharmacology 76inhibition of endogenous heat shock protein 70 attenuates inducible nitric oxide synthase induction via disruption of heat shock protein 70/na( ) /h( ) exchanger 1-ca(2 ) -calcium-calmodulin-dependent protein kinase ii/transforming growth factor �-activated kinase 1-nuclear factor-�b signals in bv-2 microglia7immunobiology 7{methylene blue attenuates inos induction through suppression of transcriptional factor binding amid inos mrna transcription7j cell biochem7
neurosci lett7%todorovic, nevena; filipovic, dragana7olactobacillus raises in vitro anticancer effect of geniposide in hsc-3 human oral squamous cell carcinoma cells7&international journal of neuroscience 7cidentification of functional farnesoid x receptors in brain neurons7 febs lett7]bile acid signaling pathways from the enterohepatic circulation to the central nervous system7�mechanism of 2,3,4',5-tetrahydroxystilbene 2-o-�-d-glucoside-induced upregulation of glutamate transporter 1 protein expression in mouse primary astrocytes7pharmacology7e
stein, dirson j.; vasconcelos, mailton f.; albrechet-souza, lucas; i{.cd7 odunewu-aderibigbe, ayodeji; fliegel, larry7e
amith, schammim ray; vincent, krista marie; wilkinson, jodi marie; i{.cd7'
zhou, xiang; liu, yong; huang, yang; i{.%&7&
yu, weihua; zhang, xiaodi; wu, hao; i{.$%7#
ji, yawei; guo, xin; zhang, zhe; i{.!"7,
ren, ying; wang, jin-liang; zhang, xiang; i{.* 7#
song, qiuyi; liu, lulu; yu, jin; i{.!"76
takakuwa, shiho; mizuno, natsumi; takano, takayuki; i{.4571
ahn, huijeong; kang, seung goo; yoon, sung-il; i{./07
zhang, xu; cheng, qianni; wang, yixiang; i{.)*7(
cheng, zhou; xu, hui; wang, xiaoping; i{.&'7%
jiang, qin; yang, manyi; qu, zhan; i{.#$< 7$
xu, chao; fu, feng; li, xiaohong; i{."#7;
mertens, kim l.; kalsbeek, andries; soeters, maarten r.; i{.9:7-
abou-gharbia, m.; blass, b.; childers, w.; i{. ,7pmicroglia loss contributes to the development of major depression induced by different types of chronic stresses7
neurochem res7 �^�s
���n_�e�z7
���n_�e�z7voskressensky, leonid g.7v�ёns7# li, yanwu; jin, xingai; mao, limin7$xu, jun; chen, hu-biao; li, song-lin7(lian, mengqiao; sun, yuchao; lin, yuan; 7)wang, jianhui; liu, yang; cheng, xiaorui;7-liu, xing-yan;�wang, huai-you;�li, xue-qing;�
7(zhang, xia; yin, jintuo; liang, caijuan;7%yuan, lin; zhang, yuqian; liao, man; 7you, zhengchen7tan, chunxiang7 jiang, bo7chen, xiangfan7 chen, zhuo7
kumar, sunil7 lin, chien-liang7
liu, fengguo7wu, jingjing7
�y�ez7�ns�s�7zrecent advances on aptamer-based biosensors to detection of platelet-derived growth factor7biosensors and bioelectronics7znasrin razmi, behzad baradaran, maryam hejazi, mohammad hasanzadeh, jafar mosafer, ahad mokhtarzadeh, miguel de la guardia7�blueberry phenolics reduce gastrointestinal infection of patients with cerebral venous thrombosis by improving depressant-induced autoimmune disorder via mir-155-mediated brain-derived neurotrophic factor7front pharmacol72xu n, meng h, liu t, feng y, qi y, zhang d, wang h7numakawa t, odaka h, adachi n7br j pharmacol7cell physiol biochem76he x, yang l, wang m, zhuang x, huang r, zhu r, wang s7int j neuropsychopharmacol7_l�l7pharmacol biochem behav7gantidepressant-like effects of ginsenoside rg5 in mice: involving of hippocampus bdnf signaling pathway7"xu d, wang c, zhao w, gao s, cui z7 j nat med7�saffron (crocus sativus l.) tea intake prevents learning/memory defects and neurobiochemical alterations induced by aflatoxin b1 exposure in adult mice7$linardaki zi, lamari fn, margarity m7cell mol neurobiol7pandey s, garabadu d7yp7c3 inhibits gsk3� activation to protect dopaminergic neurons against neurotoxin-induced cell death in vitro and in vivo70gu c, zhang y, hu q, wu j, ren h, liu cf, wang g7cns neurol disord drug targets7ishevtsova ef, vinogradova dv, neganova me, avila-rodriguez m, ashraf gm, barreto ge, bachurin so, aliev g7xeffect of agomelatine on memory deficits and hippocampal gene expression induced by chronic social defeat stress in mice7sci rep7umartin v, alla�li n, euvrard m, marday t, riffaud a1, franc b, moca�r e, gabriel c, fossati p, lehericy s, lanfumey l7dtherapeutic applications of the versatile fatty acid mimetic wy146437expert opin ther pat7pollinger j, merk d7>synthesis and bioevaluation of novel analogues of justicidin amedicinal chemistry researchu����,{n �tan optimized and general synthetic strategy to prepare arylnaphthalene lactone natural products from cyanophthalides%european journal of organic chemistry,kim, taejung; jeong, kyu hyuk; kang, ki sungbsynthesis, cytotoxicity and pro-apoptosis of novel benzoisoindolin hydrazones as anticancer agents"chemical & pharmaceutical bulletin�podophyllum derivatives containing fluorine atom in the 3-position of 2-aminopyridine improved the antitumor activity by inducing p53-dependent apoptosis
wang, huai�synthesis and evaluation of aroylthiourea derivatives of 4-�-amino-4'- o-demethyl-4-desoxypodophyllotoxin as novel topoisomerase ii inhibitors'european journal of medicinal chemistryofacile synthesis of substituted arylthioureas in the presence of sodium hydridejournal of chemical research cao, qiang; liu, fang; wang, min@recent advances in the chemistry and biology of podophyllotoxinschemistry-a european journal yu, xiang; che, zhiping; xu, huilsynthesis and antitumor activities of chiral dipeptide thioureas containing an alpha-aminophosphonate moiety$liu, jingzi; liao, peng; hu, junfengvsynthesis and antitumor activity of novel aroylthiourea derivatives of podophyllotoxininvestigational new drugsmantitumor activity of portulaca oleracea l. polysaccharide on hela cells through inducing tlr4/nf-b signaling-nutrition and cancer-an international journal"zhao, rui; zhang, tao; ma, baoling^synthesis and bioactivity of pyrazolo [1,5-a] pyrimidine derivatives as novel c-met inhibitors$chinese journal of organic chemistryu������� �|a concise [3 3] heteroaromatization synthetic strategy afford dicarboxamide functionalized novel pyrazolo[1,5- a]pyrimidines!journal of heterocyclic chemistry<patel, anilkumar s.; kapuriya, naval p.; naliapara, yogesh tqsynthesis and bioevaluation of novel arylnaphthalene lignans as anticancer agentstcancer with low cathepsin d levels is susceptible to vacuolar (h )-atpase inhibitioncancer science8kitazawa, satoshi; nishizawa, satoru; nakagawa, hideyuki�development of novel beta-carboline-based hydroxamate derivatives as hdac inhibitors with dna damage and apoptosis inducing abilitiesmedchemcomm&liu, ji; wang, tingting; wang, xinyangdhy-1 induce g2/m cell cycle arrest in human colon cancer cells via atr-chk1-cdc25c and weel pathwayscancer science�chalcone flavokawain b induces autophagic-cell death via reactive oxygen species-mediated signaling pathways in human gastric carcinoma and suppresses tumor growth in nude micearchives of toxicology2017.10=chang, chia-ting; hseu, you-cheng; thiyagarajan, varadharajan�mxi1-0 regulates the growth of human umbilical vein endothelial cells through extracellular signal-regulated kinase 1/2 (erk1/2) and interleukin-8 (il-8)-dependent pathways%wu, weiling; hu, zhenzhen; wang, feng_synthesis and identification of cytotoxic diphyllin glycosides as vacuolar h -atpase inhibitors�cleistanthin a inhibits the invasion and metastasis of human melanoma cells by inhibiting the expression of matrix metallopeptidase-2 and-9oncology letters$pan, sheng; cai, hengji; gu, lixiongt1,3,5-triazine inhibitors of histone deacetylases: synthesis and biological activity�5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2- amine (pqr309), a potent, brain-penetrant, orally bioavailable, pan class i pi3k/mtor inhibitor as clinical candidate in oncologyjournal of medicinal chemistry=beaufils, florent; cmiljanovic, natasa; cmiljanovic, vladimir{design and synthesis of c3-substituted beta-carboline-based histone deacetylase inhibitors with potent antitumor activitieschemmedchem ling, yong; feng, jiao; luo, lin ma, peng-kai; wei, bao-hong; cao, yan-ling;7�
02,3,4',5-tetrahydroxystilbene-2-o-�-d-glucosid< e inhibits platelet-derived growth factor-induced proliferation of vascular smooth muscle cells by regulating the cell cycle. 08
0clinical and experimental pharmacology and physiology 0^
0
antidepressant-like effects of ginsenoside rg2 in a chronic mild stress model of depression0
0brain research bulletin0�ren, y (ren, ying); wang, jl (wang, jin-liang) ; zhang, x (zhang, xiang) ; wang, h (wang, hao) ; ye, y (ye, ying) ; song, l (song, lu); wang, yj (wang, ying-jie) ; tu, mj (tu, meng-jue); wang, ww (wang, wei-wei) ; yang, l (yang, lan); jiang, b (jiang, bo)acta pharmacologica sinica:zhang, m (zhang, meng) ; yu, lm (yu, li-ming) ; zhao, h (zhao, hang) ; zhou, xx (zhou, xuan-xuan) ; yang, q (yang, qian) ; song, f (song, fan) ; yan, l (yan, li) ; zhai, me (zhai, meng-en) ; li, by (li, bu-ying) ; zhang, b (zhang, bin); jin, zx (jin, zhen-xiao) ; duan, wx (duan, wei-xun); wang, sw (wang, si-wang)|aliskiren protects against myocardial ischaemia-reperfusion injury via an endothelial nitric oxide synthase dependent manner5clinical and experimental pharmacology and physiology�chen, y (chen, yu); meng, gl (meng, guoliang) ; bai, wl (bai, wenli) ; ma, y (ma, yan) ; xie, lp (xie, liping) ; altaf, n (altaf, naila) ; qian, yn (qian, yanning) ; han, y (han, yi) ; ji, y (ji, yong)�2,3,4',5-tetrahydroxystilbene-2-o-�-d-glucoside inhibits proliferation of vascular smooth muscle cells: involvement of no/cgmp/pkg pathway.�the effect of 2,3,4',5-tetrahydroxystilbene-2-0-�-d glucoside on neointima formation in a rat artery balloon injury model and its possible mechanisms. european journal of pharmacology�the effect of 2,3,4',5-tetrahydroxystilbene-2-o-�-d-glucoside on pressure overload-induced cardiac remodeling in rats and and its possible mechanism.
planta medica�2, 3, 5, 4-tetrahydroxystilbene-2-o--d-glucoside prevention of lipopolysaccharide-induced depressive-like behaviors in mice involves neuroinflammation and oxido-nitrosative stress inhibitionbehavioural pharmacology\chen, z (chen, zhuo) ; huang, c (huang, chao); he, hy (he, haiyan); ding, wb (ding, wenbin):zhang, m (zhang, meng) ; yu, lm (yu, li-ming) ; zhao, h (zhao, hang) ; zhou, xx (zhou, xuan-xuan) ; yang, q (yang, qian); song, f (song, fan) ; yan, l (yan, li) ; zhai, me (zhai, meng-en) ; li, by (li, bu-ying) ; zhang, b (zhang, bin); jin, zx (jin, zhen-xiao) ; duan, wx (duan, wei-xun) ; wang, sw (wang, si-wang)�tetrahydroxystilbene glycoside improves microvascular endothelial dysfunction and ameliorates obesity-associated hypertension in obese zdf rats via inhibition of endothelial autophagy$cellular physiology and biochemistry�dong, qq (dong, qianqian) ; xing, wj (xing, wenjuan) ; su, ff (su, feifei) ; liang, xy (liang, xiangyan); tian, f (tian, fei) ; gao, f (gao, feng) ; wang, sw (wang, siwang) ; zhang, hf (zhang, haifeng)}salusin-� induces smooth muscle cell proliferation by regulating cyclins d1 and e expression through mapks signaling pathways'journal of cardiovascular pharmacology.zmacrophage differentiation induced by pma is mediated by activation of rhoa/rock signaling!journal of toxicological sciencesoyang, lf (yang, lifeng) ; dai, f (dai, fan) ; tang, l (tang, lian); le, yl (le, yulan) ; yao, wj (yao, wenjuan)�song, qy (song, qiuyi) ; liu, ll (liu, lulu) ; yu, j (yu, jin) ; zhang, jy (zhang, jingyao) ; xu, mt (xu, mengting) ; sun, ll (sun, linlin) ; luo, hq (luo, huiqin) ; feng, zs (feng, zhaosong); meng, gl (meng, guoliang)�the cardiovascular functions of salusin- mediated by muscarinic receptors, glutamate receptors or l-type calcium channels within the rostral ventrolateral medulla of rats!microscopy research and technique�xie, fj (xie, fu-jia) ; chai, c (chai, chen) ; zhu, p (zhu, ping); li, b (li, bin) ; cai, hy (cai, hong-yan); lu, y (lu, yan); cao, n (cao, nong)�effect of salusin-� on peroxisome proliferator-activated receptor gamma gene expression in vascular smooth muscle cells and its possible mechanism%cellular physiology and biochemistry oantidepressant-like effects of ginsenoside rg3 in mice via activation of the hippocampal bdnf signaling cascadejournal of natural medicines�you, zc (you, zhengchen); yao, q (yao, qi) ; shen, jh (shen, jianhong); gu, zk (gu, zhikai) ; xu, h (xu, hui) ; wu, zh (wu, zhonghua) ; chen, cj (chen, chuanjun) ; li, lz (li, luozhu)xthe association of circulating mir29b and interleukin-6 with subclinical atherosclerosis�huang, yq (huang, yu-qing) ; li, j (li, jie) ; chen, jy (chen, ji-yan) ; zhou, yl (zhou, ying-ling) ; cai, ap (cai, an-ping) ; huang, c (huang, cheng) ; feng, yq (feng, ying-qing)�salusin-beta is involved in diabetes mellitus-induced endothelial dysfunction via degradation of peroxisome proliferator-activated receptor gamma)oxidative medicine and cellular longevity�sun, hj (sun, hai-jian) ; chen, d (chen, dan); wang, py (wang, pei-yao) ; wan, my (wan, ming-yu); zhang, cx (zhang, chen-xing); zhang, zx (zhang, zhi-xuan) ; lin, w (lin, wei) ; zhang, f (zhang, feng)�ppar-gamma is involved in the protective effect of 2,3,4 ',5-tetrahydroxystilbene-2-o-beta-d-glucoside against cardiac fibrosis in pressure-overloaded ratsnovel anti-fibrotic therapiesfrontiers in pharmacologyemcvicker, bl (mcvicker, benita l.) ; bennett, rg (bennett, robert g.)jyixinshu ameliorates hippocampus abnormality induced by heart failure via the ppar gamma signaling pathwayrsc advances�xian, mh (xian, minghua) ; wang, tt (wang, tingting) ; zhang, w (zhang, wen) ; gao, jh (gao, jinhuan) ; zhang, y (zhang, yi); li, df (li, defeng) ; wei, jy (wei, junying) ; yang, hj (yang, hongjun)kdihydromyricetin ameliorates atherosclerosis in ldl receptor deficient miceatherosclerosistanti-atherosclerotic effect of hesperidin in ldlr-/- mice and its possible mechanismysun, yz (sun, ye-zi) ; chen, jf (chen, jian-fei); shen, lm (shen, li-min); zhou, j (zhou, ji) ; wang, cf (wang, cui-fang)5evidence-based complementary and alternative medicine�li, hl (li, hongliang) ; li, qs (li, qisheng) ; liu, zw (liu, zhaowen) ; yang, k (yang, kai); chen, zx (chen, zhixi) ; cheng, ql (cheng, qilai) ; wu, lh (wu, longhuo)
li, xin; niu, xiangheng; zhang, wenchi; i{.)*79
burrows, nathan d.; harvey, samantha; idesis, fred a.; i{.7879
burrows, nathan d.; harvey, samantha; idesis, fred a.; i{.7870
shajari, daryush; bahari, ali; gill, pooria; i{../76
kumar, vikas; mishra, narendra k.; gupta, shradhey; i{.457$
wang, lei; li, dong; hao, yongwei; i{#7zsize-dependent facilitation of cancer cell targeting by proteins adsorbed on nanoparticles7"acs applied materials & interfaces7ςؚf7rcolloidal gold nanoparticles induce < changes in cellular and subcellular morphology7
acs nano 7@ma, xiaowei; hartmann, raimo; jimenez de aberasturi, dorleta; i{.7qerythrocyte membrane-coated upconversion nanoparticles with minimal protein adsorption for enhanced tumor imaging7 rao, lang; meng, qian-fang; bu, lin-lin; i{.7yeffects of 2,3,4 ,5-tetrahydroxystilbene-2-0-�-d-glucoside on vascular
endothelial dysfunction in atherogenic-diet rats
7planta medicinal7 _o7�
tetrahydroxystilbene glucoside isolated from polygonum multiflorum thunb. demonstrates osteoblast differentiation promoting activity7&experimental and therapeutic medicine 7$zheng, yayuan; li, jin; wu, jingkai;7b
current pharmacological developments in 2,3,4', 5-tetrahydroxystilbene 2-o-beta-d-glucoside (tsg)7#european journal of pharmacology 7$wu, jingjing; hu, wenfeng; gong, yu;7 ren, ying; wang, jin-liang; zhang, xiang; 7k
polygonum multiflorum water extract protects against nitric oxide by lps-induced in raw 264.7 macrophages.7biomedical research-india 74 lin, chien-liang; hsieh, shu-ling; wu, chih-chung; 7�inhibition of calcium-calmodulin-dependent kinase ii suppress cardiac
fibroblast proliferation and extracellular matrix secretion
7j cardiovasc pharmacol7�ca2 /calmodulin-dependent protein kinase ii beta and ii delta mediate tgf beta-induced transduction of fibronectin and collagen in human pulmonary fibroblasts7gamerican journal of physiology-lung cellular and molecular physiology 7 mukherjee, subhendu; sheng, wei; sun, rui; 7�
edaravone inhibits pressure overload-induced cardiac fibrosis and dysfunction by reducing expression of angiotensin ii at1 receptor7&drug design development and therapy 7& zhang, wei-wei; bai, feng; wang, jin;7o
aristoyunnolin h attenuates extracellular matrix secretion in cardiac fibroblasts by inhibiting calcium influx7 archives of pharmacal research 7/chen, shao-rui; zhang, wen-ping; bao, jing-mei;7�ca2 d calmodulin-dependent protein kinase ii� orchestrates g-protein-coupled
receptor and electric �eld stimulation-induced cardiomyocyte hypertrophy
7 _o7i
camkii delta meditates phenylephrine induced cardiomyocyte hypertrophy through store-operated ca2 entry7cardiovascular pathology 7!ji, yawei; guo, xin; zhang, zhe; 7�2,3,4',5-tetrahydroxystilbene-2-0-beta-d-glucoside inhibits platelet-derived growth
factor-induced proliferation of vascular smooth muscle cells by regulating cell cycle.
7clin exp pharmacol physiol.7\
antidepressant-like effects of ginsenoside rg2 in a chronic mild stress model of depression7brain research bulletin 7)ren, ying; wang, jin-liang; zhang, xiang;7acta pharmacologica sinica 7& zhang, meng; yu, li-ming; zhao, hang;7}
aliskiren protects against myocardial ischaemia-reperfusion injury via an endothelial nitric oxide synthase dependent manner78clinical and experimental pharmacology and physiology 7&chen, yu; meng, guoliang; bai, wenli; 7pharmacology 7$chen, xiangfan; hu, wenfeng; lu, xu;7�2,3,42 ,5-tetrahydroxystilbene-2-o-b-d-glucoside inhibits angiotensin
ii-induced cardiac �broblast proliferation via suppression of the reactive
oxygen species extracellular signal-regulated kinase 1/2 pathway
7clin exp pharmacol physiol.7_
luteolin: a flavonoid that has multiple cardio-protective effects and its molecular mechanisms7frontiers in pharmacology 7*luo, yuanyuan; shang, pingping; li, dongye7& wu, jingjing; hu, wenfeng; gong, yu; 7�
grk2 mediates arginine vasopressin-induced interleukin-6 production via nuclear factor-kappa b signaling neonatal rat cardiac fibroblast7molecular pharmacology 7) xu, feifei; sun, shuzhen; wang, xiaojun;7!european journal of pharmacology 7song, qiuyi; liu, lulu; yu, jin7�astragaloside iv inhibits isoprenaline-induced cardiac fibrosis by targeting the reactive oxygen species/mitogen-activated protein kinase signaling axis7molecular medicine reports 7) dai, hongliang; jia, guizhi; lu, meili; 7�
2,3,5,4 '-tetrahydroxystilbene-2-o-beta-d-glucoside protects murine hearts against ischemia/reperfusion injury by activating notch1/hes1 signaling and attenuating endoplasmic reticulum stress7acta pharmacologica sinica 7%zhang, meng; yu, li-ming; zhao, hang;7z
grk2/beta-arrestin mediates arginine vasopressin-induced cardiac fibroblast proliferation7,chen, yunxuan; xu, feifei; zhang, lingling; 7�ho-1 is essential for tetrahydroxystilbene glucoside mediated mitochondrial biogenesis and anti-inflammation process in lps-treated raw264.7 macrophages7-oxidative medicine and cellular longevity 7#yu, weihua; zhang, xiaodi; wu, hao;7�
effect of testosterone on the proliferation and collagen synthesis of cardiac fibroblasts induced by angiotensin ii in neonatal rat7bioengineered 7( yang, xiaocun; wang, ying; yan, shuxun;7gelectrical field stimulation induces cardiac fibroblast proliferation through calcineurin-nfat pathway.7can j physiol pharmacol.7e
soluble epoxide hydrolase inhibition protected against angiotensin ii-induced adventitial remodeling7scientific reports 7!zhou, chi; huang, jin; li, qing; 7! song, qiuyi; liu, lulu; yu, jin;7z
grk2/beta-arrestin mediates arginine vasopressin-induced cardiac fibroblast proliferation77clinical and experimental pharmacology and physiology 7 chen, yunxuan; xu, feifei; zhang, lingling;7[mir-17-3p inhibits angiogenesis by downregulating flk-1 in the cell growth signal pathway. 7
j vasc res7~
microrna-17-3p promotes keratinocyte cells growth and metastasis via targeting myot and regulating notchl/nf-kappa b pathways7
pharmazie 7*yan, hongshan; song, kunxiu; zhang, guohui7;
cancer hallmarks and micrornas: the therapeutic connection7mirna and cancer 7* van roosbroeck, katrien; calin, george a.7��-n-heterocyclic thiosemicarbazone fe(iii) complex: characteri< zation of its antitumor activity and identification of anticancer mechanism7eur j med chem.7�effects of terminal substitution and iron coordination on antiproliferative activity of l-proline-salicylaldehyde-thiosemicarbazone hybrids7(european journal of inorganic chemistry 7=milunovic, miljan n. m.; dobrova, aliona; novitchi, ghenadie;7ostructure and biological properties of mixed-ligand cu(ii) schiff base complexes as potential anticancer agents7)european journal of medicinal chemistry 7!gou, yi; li, jinlong; fan, boyi; 7_design, synthesis and anticancer activity of novel nopinone-based thiosemicarbazone derivatives7)bioorganic & medicinal chemistry letters 7"wang, yunyun; gu, wen; shari, yu; 7�morpholine or methylpiperazine and salicylaldimine based heteroleptic square planner platinum (ii) complexes: in vitro anticancer study and growth retardation effect on e-coli7/rahman, faiz-ur; ali, amjad; khan, inam ullah; 7.rahman, faiz-ur; ali, amjad; khan, inam ullah;7pdeveloping anticancer ferric prodrugs based on the n-donor residues of human serum albumin carrier iia subdomain7
j med chem7 _o���7�synthesis, crystal structure and antiproliferative mechanisms of 2-acetylpyridine-thiosemicarbazones ga(iii) with a greater selectivity against tumor cells7#journal of inorganic biochemistry 7$qi, jinxu; zheng, yunyun; qian, kun;7�albumin based versatile multifunctional nanocarriers for cancer therapy: fabrication, surface modification, multimodal therapeutics and imaging approaches7imaterials science & engineering c-materials for biological applications 7$kudarha, ritu r.; sawant, krutika k.7�synthesis and structure elucidation of novel salophen-based dioxouranium(vi) complexes: in-vitro and in-silico studies of their dna/bsa -binding properties and anticancer activity7(european journal of medicinal chemistry 7eebrahimipour, s. yousef; mohamadi, maryam; mahani, masoud torkzadeh; 7�
effects of terminal substitution and iron coordination on antiproliferative activity of l-proline-salicylaldehyde-thiosemicarbazone hybrids7=milunovic, miljan n. m.; dobrova, aliona; novitchi, ghenadie;7�cu(ii), ga(iii) and in(iii) complexes of 2-acetylpyridine n(4)-phenylthiosemicarbazone: synthesis, spectral characterization and biological activities7medchemcomm 7&wang, yu-ting; fang, yan; zhao, meng; 7�
novel 2-pyridinecarboxaldehyde thiosemicarbazones ga(iii) complexes with a high antiproliferative activity by promoting apoptosis and inhibiting cell cycle
7%qi, jinxu; deng, jungang; qian, kun; 7d
design an anticancer copper(ii) pro-drug based on the flexible iia subdomain of human serum albumin7%zhang, yao; zhang, zhenlei; gou, yi; 7�design of an anticancer copper(ii) prodrug based on the lys199 residue of the active targeting human serum albumin nanoparticle carrier7molecular pharmaceutics 7$gou, yi; zhang, yao; zhang, zhenlei;7f
strategies for preparing albumin-based nanoparticles for multifunctional bioimaging and drug delivery7
theranostics 7an, fei-fei; zhang, xiao-hong7�rescue of cardiac failing and remodeling by inhibition of pp1� is associated with suppression of the asf-mediated splicing of camkii�7*ren, ying; wang, jin-liang; zhang, xiang; 7 song, qiuyi; liu, lulu; yu, jin;7�cryptotanshinone inhibits the growth and invasion of colon cancer by suppressing inflammation and tumor angiogenesis through modulating mmp/timp system, pi3k/akt/mtor signaling and hif-1� nuclear translocation7 international immunopharmacology7scientific reportsoanimal models of chronic pain: advances and challenges for clinical translation journal of neuroscience researchcburma, nicole e.; leduc-pessah, heather; fan, churmy y.; tuan trang1gn7
���n_�e�z7jantinociceptive effects of sinomenine in a rat model of postoperative pain7british journal of pharmacology7sdissolving microneedles integrated with liquid crystals facilitate transdermal delivery of sinomenine hydrochloride7"journal of pharmaceutical sciences7�gui, zhiping; wu, xingxing; wang, shuyan; cao, yingji; wan, jun; shan, qianqian; yang, zhuanzhuan; zhang, jiwen; gui, shuangying7�sinomenine hydrochloride inhibits human glioblastoma cell growth through reactive oxygen species generation and autophagy-lysosome pathway activation: an in vitro and in vivo study7 international journal of molecular sciences7ejiang, yumao; jiao, yue; wang, zhiguo; li, tao; liu, yang; li, yujuan; zhao, xiaoliang; wang, danqiao7`sinomenine produces peripheral analgesic effects via inhibition of voltage-gated sodium currents7neuroscience7xlee, jeong-yun;yoon, seo-yeon;�won, jonghwa;�kim, han-byul;�kang, youngnam;�oh, seog bae7hantinociceptive effects of curcumin in a rat model of postoperative pain7scientific reports71gn7bdendrosomal nanocurcumin prevents morphine self-administration behavior in rats despite ca1 damage7behavioural pharmacology7�noroozi, j (noroozia, jalaleden)[ 1 ] ; hassanpour-ezatti, m (hassanpour-ezatti, majid)[ 1 ] ; alaei, ha (alaei, hojjat a.)[ 2 ]7�oral administration of curcumin attenuates visceral hyperalgesia through inhibiting phosphorylation of trpv1 in rat model of ulcerative colitis7molecular pain7�yang, m (yang, mei)[ 1,2 ] ; wang, j (wang, juan)[ 1,2 ] ; yang, cx (yang, chunxue)[ 3 ] ; han, hx (han, hongxiu)[ 3 ] ; rong, wf (rong, weifang)[ 1,2 ] ; zhang, gh (zhang, guohua)7�comparison of the pro-postoperative analgesia of intraoperative dexmedetomidine with and without loading dose following general anesthesia a prospective, randomized, controlled clinical trial7medicine7�fan, w (fan, wei)[ 1 ] ; yang, hk (yang, haikou)[ 2 ] ; sun, y (sun, yong)[ 3 ] ; zhang, j (zhang, jun)[ 1 ] ; li, gm (li, guangming)[ 1 ] ; zheng, y (zheng, ying)[ 1 ] ; liu, y (liu, yi)7�characterization of metabolites of leonurine (scm-198) in rats after oral administration by liquid chromatography/tandem mass spectrometry and nmr spectrometry7the scientific world journal7�atypical protein disulfide isomerases (pdi): comparison of the molecular and catalytic properties of poplar pdi-a and pdi-m with pdi-l1a7plos one7�selles, b (selles, benjamin)[ 1,2 ] ; zannini, f (zannini, flavien)[ 1 ] ; couturier, j (couturier, jeremy)[ 1 ] ; jacquot, jp (jacquot, jean-pierre)[ 1 ] ; rouhier, n (rouhier, nicolas)7osoil contamination by metals with high < ecological risk in urban and rural areas7=international journal of environmental science and technology7�da silva, fbv (da silva, f. b. v.)[ 1 ] ; do nascimento, cwa (do nascimento, c. w. a.)[ 1 ] ; araujo, prm (araujo, p. r. m.)[ 1 ] ; da silva, fl (da silva, f. l.)[ 1 ] ; lima, lhv (lima, l. h. v.)7�the difference of superoxide dismutase levels in patient's saliva with gingivitis associated with dental plaque only before and after scaling at periodontics installation, faculty of dentistry usu7iproceedings of the international dental conference of sumatera utara 20177tsyahputra, a (syahputra, armia)[ 1 ] ; pasaribu, k (pasaribu, krisnamurthy)[ 1 ] ; pulungan, d (pulungan, dina)[ 2 ]7�characterization of metabolites in rat and liver microsomes after intravenous injection of mmaf by liquid chromatography/tandem mass spectrometry7"latin american journal of pharmacy7�tang, y (tang, yu)[ 1,2,3 ] ; wang, xy (wang, xiang-yang)[ 2,3 ] ; ma, xh (ma, xiao-hui)[ 2,3 ] ; ye, h (ye, hui)[ 1 ] ; zhou, f (zhou, fang)[ 1 ] ; wang, gj (wang, guang-ji)[ 1 ]7rmetabolic pathways and pharmacokinetics of natural medicines with low permeability7drug metabolism reviews7�zeng, m (zeng, mei)[ 1 ] ; yang, l (yang, lan)[ 1 ] ; he, d (he, dan)[ 1 ] ; li, y (li, yao)[ 1 ] ; shi, mx (shi, mingxin)[ 1 ] ; zhang, jq (zhang, jingqing)7hantinociceptive effects of sinomenine in a rat model of neuropathic pain7�sinomenine hydrochloride attenuates the proliferation, migration, invasiveness, angiogenesis and epithelial-mesenchymal transition of clear-cell renal cell carcinoma cells via targeting smad in vitro7biomedicine & pharmacotherapy7^zhao, bin; liu, lei; mao, jun; liu, kun; fan, weiwang; liu, jiheng; zhang, zhiwei; li, quanlin7�sinomenine, an alkaloid derived from sinomenium acutum potentiates pentobarbital-induced sleep behaviors and non-rapid eye movement (nrem) sleep in rodents7biomolecules & therapeutics76yoo, jae hyeon; ha, tae-woo; hong, jin tae; oh, ki-wan7ejiang, yumao; jiao, yue; wang, zhiguo; li, tao; liu, yang; li, yujuan; zhao, xiaoliang; wang, danqiao7neuroscience7lthe effect of sinomenine in diabetic neuropathic pain mediated by the p2x(3) receptor in dorsal root ganglia7purinergic signalling7�rao, sq�(rao, shenqiang)[�1�]�;�liu, sm�(liu, shuangmei)[�1�]�;�zou, lf�(zou, lifang)[�1�]�;�jia, ty�(jia, tianyu)[�1�]�;�zhao, sh�(zhao, shanhong)[�1�]�;�wu, b(wu, bing)[�1�]�;�yi, zh�(yi, zhihua)[�1�]�;�wang, sy�(wang, shouyu)[�1�]�;�xue, y�(xue, yun)[�1�]�;�gao, y�(gao, yun)[�1�]�;�xu, cs�(xu, changshui)[�1�]�;�li, gl�(li, guilin)[�1�];�xu, h�(xu, hong)[�1�]�;�zhang, cp�(zhang, chunping)[�1�]�;�liang, sd�(liang, shangdong)7zsinomenine inhibits ovarian cancer cell growth and metastasis by mediating the wnt/beta-catenin pathway via targeting mcm27rsc advances7li, hm�(li, huimin)[�1�]�;�lin, zk�(lin, zhikun)[�2�]�;�bai, yx�(bai, yuxin)[�1�]�;�chi, xm�(chi, xinming)[�4�]�;�fu, hl�(fu, hailu)[�1�]�;�sun, r�(sun, rui)[�3�]�;�liu, mz(liu, meizi)[�2�]�;�liu, x�(liu, xuan)[�1�]�;�chen, ly�(chen, liying)[�1�]�;�shao, sj�(shao, shujuan)7nligustilide prevents cognitive impairment and attenuates neurotoxicity in d-galactose induced aging mice brain7brain research7�puerarin and amlodipine improvement of d-galactose-induced impairments of behaviour and neurogenesis in mouse dentate gyrus: correlation with glucocorticoid receptor expression7neurochemical research7�li, xy (li, xinyu)[ 1 ] ; ma, jr (ma, jingrui)[ 1 ] ; xu, j (xu, jia)[ 2 ] ; zhu, ds (zhu, dashuai)[ 3 ] ; li, ar (li, anran)[ 1 ] ; che, yz (che, yongzhe)[ 3 ] ; chen, dy (chen, dongyan)[ 2 ] ; feng, xz (feng, xizeng)7yquercetin ameliorates learning and memory via the nrf2-are signaling pathway in d-galactose-induced neurotoxicity in mice73biochemical and biophysical research communications7dong, fx (dong, fuxing)[ 1 ] ; wang, s (wang, shuang)[ 2 ] ; wang, yw (wang, yiwen)[ 2 ] ; yang, x (yang, xiao)[ 2 ] ; jiang, jl (jiang, jiali)[ 2 ] ; wu, dj (wu, dejian)[ 2 ] ; qu, xb (qu, xuebin)[ 1 ] ; fan, hb (fan, hongbin)[ 3 ] ; yao, rq (yao, ruiqin)[ 1 ]7�d-galactose-induced brain ageing model: a systematic review and meta-analysis on cognitive outcomes and oxidative stress indices7plos one7�sadigh-eteghad, s (sadigh-eteghad, saeed)[ 1 ] ; majdi, a (majdi, alireza)[ 1 ] ; mccann, sk (mccann, sarah k.)[ 2 ] ; mahmoudi, j (mahmoudi, javad)[ 1 ] ; vafaee, ms (vafaee, manouchehr s.)[ 3 ] ; macleod, mr (macleod, malcolm r.)[ 4 ]7{protective effect of sfe-co2 of ligusticum chuanxiong hort against d-galactose-induced injury in the mouse liver and kidney7rejuvenation research7imo, zz (mo, zhi-zhun)[ 1,2 ] ; liu, yh (liu, yu-hong)[ 1 ] ; li, cl (li, cai-lan)[ 1 ] ; xu, lq (xu, lie-qiang)[ 1 ] ; wen, ll (wen, ling-ling)[ 1 ] ; xian, yf (xian, yan-fang)[ 2 ] ; lin, zx (lin, zhi-xiu)[ 2 ] ; zhan, jyx (zhan, janis ya-xian)[ 1 ] ; chen, jn (chen, jian-nan)[ 1 ] ; xu, ff (xu, fang-fang); su, zr (su, zi-ren �7�dietary krill oil enhances neurocognitive functions and modulates proteomic changes in brain tissues of d-galactose induced aging mice7food & function7�cheong, lz (cheong, ling-zhi)[ 1 ] ; sun, tt (sun, tingting)[ 1 ] ; li, yy (li, yanyan)[ 2 ] ; zhou, j (zhou, jun)[ 1 ] ; lu, cy (lu, chenyang)[ 1 ] ; li, y (li, ye)[ 1 ] ; huang, zb (huang, zhongbai)[ 1 ] ; su, xr (su, xiurong)7ieffects of angelica oil and the isolated butylphthalides on glutamate-induced neurotoxicity in pc12 cells7records of natural products7�liu, ls�(liu, lu-si)[�1,2�]�;�peng, c�(peng, cheng)[�1,2�]�;�zhou, qm�(zhou, qin-mei)[�1,2�]�;�xiong, l�(xiong, liang)[�1,2�]�;�guo, l�(guo, li)[�1,2�]�;�wang, yn(wang, ya-nan)[�3,4�]�;�dai, o�(dai, ou)[�1,2�]7fnatural products against alzheimer's disease: pharmaco-therapeutics and biotechnological interventions7biotechnology advances7�dey, a (dey, abhijit)[ 1 ] ; bhattacharya, r (bhattacharya, raktim)[ 1 ] ; mukherjee, a (mukherjee, anuradha)[ 2 ] ; pandey, dk (pandey, devendra kumar)[ 3 ]7textract of fructus cannabis ameliorates learning and memory impairment induced by d-galactose in an aging rats model7�chen, ny (chen, ning-yuan)[ 1 ] ; liu, cw (liu, cheng-wu)[ 1,2 ] ; lin, w (lin, wei)[ 3 ] ; ding, y (ding, yi)[ 1 ] ; bian, zy (bian, zhang-ya)[ 1 ] ; huang, l (huang, ling)[ 1 ] ; huang, h (huang, hao)[ 1 ] ; yu, kh (yu, kai-hui)[ 1 ] ; chen, sb (chen, si-bang)[ 4 ] ; sun, y (sun, yu)[ 4 ] ; wei, l (wei, lei)[ 4 ] ; peng, jh (peng, jun-hua)[ 1,2 ] ; pan, sl (pan, shang-ling)[ 1,2 ] 76pharmacokinetics of botanical drugs and plant extracts7#mini-reviews in medicinal chemistry7�more, gpd (dominguez more, gina paola)[ 1,2 ] ; cardenas, pa (andrea cardenas, paola)[ 1 ] ; costa, gm (costa, geison m.)[ 3 ] ; simoes, cmo (simoes, claudia m. o.)[ 4 ] ; aragon, dm (marcela aragon, diana)[ 1 ]7<lintranasal cerebrolysin attenuates learning and memory impairments in d-galactose-induced senescence in mice7experimental gerontology7�pourmemar, e (pourmemar, ehsan)[ 1 ] ; majdi, a (majdi, alireza)[ 1 ] ; haramshahi, m (haramshahi, morteza)[ 1 ] ; talebi, m (talebi, mahnaz)[ 1 ] ; karimi, p (karimi, pouran)[ 1 ] ; sadigh-eteghad, s (sadigh-eteghad, saeed)[ 1 ]7u���7u���7u������7jl�q�^7=polydatin protects the respiratory system from pm2.5 exposure7
yan xiao-dani{7�intelligent "peptide-gathering mechanical arm" tames wild "trojan-horse" peptides for the controlled delivery of cancer nanotherapeutics7"acs applied materials & interfaces7�shi, nq�(shi, nian-qiu);�li, y�(li, yan);�zhang, y�(zhang, yong);�shen, n�(shen, nan);�qi, l�(qi, ling);�wang, sr�(wang, shu-ran)�;�qi, xr�(qi, xian-rong)7lnon-viral gene delivery systems: hurdles for bench-to-bedside transformation7 pharmazie7�helal, na�(helal, n. a.);�osami, a�(osami, a.);�helm, a�(helm, a.);�mcdonald, t�(mcdonald, t.);�shaaban, la�(shaaban, l. a.);�nounou, mi�(nounou, m. i.)7"nanomaterials for cancer therapies7nanotechnology reviews7<zhou, q (zhou, qing); zhang, l (zhang, li); wu, h (wu, hong)7/advances in quantum dot-mediated sirna delivery7chinese chemical letters7�he, zy (he, zhi-yao)[ 1,2,3 ] ; jin, zh (jin, zhao-hui)[ 1,2,3 ] ; zhan, m (zhan, mei)[ 1,2,3 ] ; qin, z (qin, zhou)[ 1,2,3 ] ; li, z (li, zhi)[ 4 ] ; xu, t (xu, ting)[ 1,2,3 ]7wsirna crosslinked nanoparticles for the treatment of inflammation- induced liver injury7advanced science7�tang, yq (tang, yaqin)[ 1 ] ; zeng, zy (zeng, ziying)[ 1 ] ; he, x (he, xiao)[ 1 ] ; wang, tt (wang, tingting)[ 1 ] ; ning, xh (ning, xinghai)[ 2 ] ; feng, xl (feng, xuli)[ 1 ]7aa review of drug delivery systems based on nanotechnology and green chemistry: green nanomedicine7%international journal of nanomedicine7�jahangirian, h�(jahangirian, hossein);�lemraski, eg�(lemraski, ensieh ghasemian);�webster, tj�(webster, thomas j.);�rafiee-moghaddam, r�(rafiee-moghaddam, roshanak);�abdollahi, y�(abdollahi, yadollah)7lph-responsive hybrid quantum dots for targeting hypoxic tumor sirna delivery7journal of controlled release7ghongyan zhu, shengyu zhang, yongling, guoliang meng, yu yang, wei zhang7�
4����c�n���e�s�n�t
yps�n�\b�0�vu_0ck�e��u�b\o�usmo:nws�'yf[�vu�b� ��vq-n���e�s�n�y�bn�nny�[8hts_ss�؏0��sci0ei0cpci-s6eu_�v���e��n�sq_�t�vp[0jcrr:s�~ r��c�ob!h�vfn���qwq�v�vsq�h"}��f0�h"}�nf[b�:nusmo�
n�c6e*n�n3u����k�n�np��qwq1�n��f �����eh�����c�o�e��
t�-n�e��
t
nzp�h"}�kxh��e�nx���l g6eu_�v�e�z��
n��kx�q0
�7`2�kxh��e���~n