包小峰-yb体育官方
师资介绍
包小峰:男,1979年9月生,教授,南通大学药学院副院长,微生物与生化药学研究生导师,江苏省高校“青蓝工程”中青年学术带头人,南通市“226工程”第二层次培养对象,中国微生物学会人兽共患病病原学专业委员会委员,长期从事微生物感染与防治相关领域的研究。近年来主持完成2项国家自然科学基金项目,近年来在pnas、aac、j bacteriol等国内外权威杂志发表学术论文30余篇。
1. 教育经历:
(1) 2002.09–2007.06南京大学,生物化学与分子生物学,博士,导师:华子春、沈萍萍
(2) 1998.09–2002.06南京大学,生物制药工程,学士
2. 科研与学术工作经历:
(1) 2013.01-至今南通大学,药学院,教授
(2) 2011.08-2012.12美国新泽西医学和牙科大学,药理学系,研究助理
(3) 2007.09-2011.08美国新泽西医学和牙科大学,博士后,导师:huizhou fan
3. 主持科研项目及人才计划项目情况:
南通市基础科学研究项目,jc2019097,抗衣原体药物的筛选与作用机制研究,2019/07-2021/06,3万元,完成,主持
南通市第五期“226工程”第二层次培养对象,2018/08-2021/07,完成
国家自然科学基金青年项目,31400165,靶向单基因模型构建与新型小分子化合物cb抗衣原体分子机制研究,2015/01-2017/12,23万元,完成,主持
国家自然科学基金面上项目,31370209,grga在衣原体生长发育过程中的基因转录调控机制的研究,2014/01-2017/12,80万元,已结题,主持
江苏省高校“青蓝工程”中青年学术带头人,2014/06-2017/06,已完成
4. 近5年发表论文和专利申请:
miao sun#, wenchengyang bao#, chengyu huang, changliang zhang, guangxian wang, runxin wang, jiangyu li, shaunroux, qian li, dongmei zou, kai ma*,xiaofeng bao*. a novel probiotic formula, biocg, protects against alzheimer’s-related cognitive deficits via regulation of dendritic spine dynamics. curr alzheimer res 2021
min ni#, shunxin xu#, ziyi liu, yin xue, wenxia xie, shengju yang*, lingyan liu, xiaofeng bao*. inhibitory activity of pyrroloisoxazolidine derivatives against chlamydia trachomatis. biomed res int 2021 mar 13;2021:8889247.
miao sun#, kai ma#, jie wen, guangxian wang, changliang zhang, qi li, xiaofeng bao*, hui wang*. a review of the brain-gut-microbiome axis and the potential role of microbiota in alzheimer's disease.j alzheimers dis2020;73(3):849-865.
xiaofeng bao#, ziyi liu#, min ni, chao xia, shunxin xu, shengju yang*, yu zhao*. synthesis and assessment of 3-substituted phenazines as novel antichlamydial agents. med chem 2020; 16:413-421.
xiaofeng bao, xiaowei yu, chao xia, ningjing yang, shengju yang*, yu zhao*. synthesis and antichlamydial activity of novel phenazines. lett drug des discov 2019; 16(2):174-181.
yin zhou, huanhuan jin, yu wu, liang chen, xiaofeng bao*, chunfeng lu*.gallic acid protects against ethanol-induced hepatocyte necroptosis via an nrf2-dependent mechanism. toxicol in vitro 2019; 57:226-232.
malhar desai, wurihan wurihan, rong di, joseph d. fondell, bryce e. nickels, xiaofeng bao*, huizhou fan*. a role for grga in regulation of σ28-dependent transcription in the obligate intracellular bacterial pathogen chlamydia trachomatis. j bacteriol 2018; pii: jb.00298-18.
jian lin li#, ningjing yang#, lei huang, dandan chen, yu zhao, m. matt tang, huizhou fan*, xiaofeng bao*. pyocyanin inhibits chlamydia infection by disabling infectivity of the elementary body and disrupting intracellular growth. antimicrob agents chemother 2018; 62(6). pii: e02260-17.
hongzhang ji#, changyue wu#, min ni, nannan feng, chan wang, yu zhao, lingyan liu, shengju yang*, xiaofeng bao*. in vitro antichlamydial activity of 1,2,3,5-tetrasubstituted pyrrole derivatives. chemotherapy 2018; 63(2):95-99.
xiaofeng bao, ying xue, chao xia, yin lu, ningjingyang, yu zhao*. synthesis and assessment of novel anti-chlamydial benzylidene acylhydrazides derivatives. lett drug des discov 2018; 15(1):31-36.
jian lin li#, dandan chen#, lei huang, min ni, yu zhao, huizhou fan, xiaofeng bao*. antichlamydial dimeric indole derivatives from marine actinomycete rubrobacter radiotolerans. planta medica 2017; 83:805-811.
申请号:cn 202110591839.7;专利名称:一种密码子优化的沙眼衣原体ctl0286基因及其应用;发明类别:c类;发明人:包小峰,陆春风,孙邈,刘书龙,解文霞,姜和;受理
申请号:cn 2020111776558;专利名称:异泽兰黄素在制备预防或治疗酒精性肝病药物中的应用;发明类别:c类;发明人:陆春风,包小峰,许文萱,李明娜,吴若曼,周莹,姜毅铭;实审
申请号:cn 2020107948354;专利名称:没食子酸在制备治疗酒精性肝病的药物中的应用;发明类别:c类;发明人:陆春风,包小峰,吴若曼,任远远,彭秀芳,姜毅铭,周莹;实审
申请号:cn 202010223202.8;专利名称:一种具有含氮侧链的吩嗪衍生物及其制备方法和应用;发明类别:c类;发明人:赵育,包小峰,朱力;实审
申请号:cn 202010145928.4;专利名称:一种山荷叶素醚类衍生物及其制备方法和应用;发明类别:c类;发明人:赵育,包小峰,朱力;实审
申请号:cn 202010075949.3;专利名称:一种山荷叶素杂环衍生物及其制备方法和应用;发明类别:c类;发明人:赵育,沈卫东,包小峰,朱力;实审