方桂花-yb体育官方
师资介绍
方桂花,女, 1990年9生,药剂学博士,南通大学药学院,讲师
研究方向:
口服递药,眼部新型给药系统,缓控释制剂
基金项目:
南通市自然科学基金,jc2019100,基于胆酸吸收途径的口服纳米递药系统构建及治疗肝癌的研究,2019-07 至 2021-06,3万元,已结题,主持
江苏省高校自然科学研究面上项目,18kjb350009,粘附性高载药量脂质载体应用于胰岛素口服传递研究,2018-07 至 2020-06,3万元,已结题,主持
江苏省自然科学基金(青年项目),bk20170445,靶向新型有机阳离子转运体的眼用前药递送系统的研究, 2017-07 至 2020/06,20万,已结题,参加
代表性论文:
(1) fang guihua and tang bo*, current advances in nano-delivery of celastrol for treating inflammation associated diseases, journal of materials chemistry b, 2020, 8(48), 10954-10965.
(2) fang guihua, tang bo*, advanced delivery strategies facilitating oral absorption of heparins, asian journal of pharmaceutical sciences, 2020, 15(4), 449-460.
(3)tang bo, qian yu, fang guihua*. development of lipid-polymer hybrid nanoparticles for improving oral absorption of enoxaparin. pharmaceutics, 2020, 12(7), 607-618.
(4) tang bo, qian yu, gou yi, cheng gang, fang guihua*, ve-albumin core-shell nanoparticles for paclitaxel delivery to treat mdr breast cancer. molecules, 2018, 23, 2760.
(5) fang guihua, zhou jing, qian yu, gou jingxin, yang xiang, tang bo*, development and evaluation of thermo-sensitive hydrogel system with nanocomplexes for prolonged subcutaneous delivery of enoxaparin, journal of drug delivery science and technology, 2018, 48 (2018), 118-124.
(5) fang guihua, tang bo, chao yanhui, xu helin, gou jingxin, zhangyu, xu hui, tang xing*,cysteine-functionalized nanostructured lipid carriers for oral delivery of docetaxel: a permeability and pharmacokinetic study. molecular pharmaceutics, 2015, 12 (7), 2384-2395.
(6) fang guihua, tang bo, chao yanhui, zhang yu*, xu hui, tang xing*, improved oral bioavailability of docetaxel by nanostructured lipid carriers: in vitro characteristics, in vivo evaluation and intestinal transport studies. rsc advances, 2015, 5(117), 96437-96447.
(7) fang guihua, tang bo, liu zitong, gou jingxin, zhangyu, xu hui, tang xing*. novel hydrophobin-coated docetaxel nanoparticles for intravenous delivery: in vitro characteristics and in vivo performance. european journal of pharmaceutical sciences, 2014, 60, 1-9.